Cancer research, trials, treatments and discoveries are going on around the world and encouraging progress is being made in many areas. Lead story this week is about the contribution of a near neighbour. (Prof Frazer is pictured above.)
That’s followed by a less encouraging discussion about cancer diagnosis – pessimistic, yes, but a realistic viewpoint none the less.
# "If you are a pessimist, you are never going to be disappointed” is a very optimistic attitude to being a pessimist.
# Seeds are the original .zip files.
# There is probably an entire factory dedicated to making 'made in china' stickers.
Qld researchers have high hopes for head-and-neck cancer treatment
(Australia) Former Australian of the Year Ian Frazer is close to starting clinical human trials on a new vaccine that could be used to treat head and neck cancers.
Admedus Immunotherapies is working with Brisbane’s Princess Alexandra Hospital on the breakthrough, which is based on the use of Professor Frazer’s human papillomavirus (HPV) vaccine.
Prof Frazer said HPV-associated cancers made up 20 per cent of all people diagnosed worldwide.
|“Unfortunately, conventional treatments are not always successful,” he said in a statement.
“Harnessing the immune system is a new way to treat these virus-associated cancers.”
Admedus Immunotherapies chief executive Neil Finlayson said the new HPV vaccine had already successfully treated tumours in mice.
“Head and neck cancer is rising in incidence, and while chemo-radiation therapy has a good prognosis, in about 20 per cent of cases the cancer will metastasise,” he said in a statement.
“While there are only 25,000 cases of HPV-associated head and neck cancers globally each year, demonstrated clinical proof of concept of the vaccine’s effectiveness in treatment would mean the HPV vaccine could potentially be used to treat all HPV-associated cancers.”
The next step is to conduct a human clinical trial in Queensland, which is due to be completed by early 2019.
Admedus Immunotherapies received a $250,000 grant from the Queensland government to carry out the trial.
Queensland Innovation Minister Leeanne Enoch said the project had the potential to become “a billion-dollar market within three years of being approved”.
“This project, in which Advance Queensland is backing one of Queensland’s leading medical researchers, has enormous potential – from saving lives around the world to reinforcing Queensland’s reputation as a place to conduct and invest in research and clinical development,” she said in a statement.
Cancer will not 'defeat' John McCain — or anyone else
(U.S.) Cancer will not defeat John McCain. And John McCain will not beat cancer. Cancer is neither an opponent nor a binary condition. A medical team finds it, cuts it out, poisons it, irradiates it and prays for the best.
If they are successful, if your stars are aligned, your cancer will go into hiding and lurk just outside the gates of good fortune for a long time.
Senator McCain is a war veteran, POW survivor and presidential candidate. His courage has never been in question. But cancer cares nothing about heroism, and only five out of 100 people outlive glioblastoma; according to the best studies available, their survival was not due to willpower or fighting spirit.
Teddy Kennedy and Beau Biden lacked for neither, and both were felled by the disease. If “battling cancer” has long been a misguided metaphor, it seems spectacularly inapposite in connection with the redoubtable John McCain.
The idea of winning or losing is just cruel. And it has been since Susan Sontag made the point 40 years ago in her classic “Illness As Metaphor.” Then, as now, support and encouragement can be salutary during hard times and health challenges, but they are not magical. Cancer is not an adversary to be conquered or outsmarted; cancer is, in author Siddhartha Mukherjee’s phrase, the emperor of all maladies.
The sooner we stop pitting humans against a disease, cease using war metaphors, the better off we all shall be, especially cancer patients and their loved ones. Many a mislabeled loser has been quietly valiant and heroic beyond belief.
When first diagnosed, unspoken shame strikes all patients: you must have smoked or drunk too much, eaten unwisely, exercised insufficiently, loved incompletely, or mangled your emotions into a sorry state.
And then, should you succumb to cancer, the unuttered implication is you did not fight doggedly enough, or you chose the wrong hospital or wrong protocol or, God forbid, the wrong God. It is all unnecessary and untrue. You do not declare war on nature; cancer has been with us since ancient Greece, when Hippocrates, the father of medicine, removed tumors around 440 BC. Just like my doctors did for me in 2015.
Tonsillar squamous cell carcinoma is not as lethal as glioblastoma, but it’s a serious disease.
Cancer of the head and neck is the sixth most common malignancy in the world.
Possessing neither the energy nor inclination to charge into battle, I surrendered after getting over the shock of the diagnosis. I surrendered to the new realities: the constant companionship of mortality and the hard work ahead.
After CAT and PET scans, I took drugs, took notes, had teeth removed, then a tonsil (by a robot) and dozens of lymph nodes. No food or water for eight days. Thirty-five radiation sessions scrambled my taste buds like eggs, burned my throat like toast, and fried my saliva glands. Talking was difficult, breathing was compromised and any social life was fantasy.
Since cancer thrives on alcohol and sugars, I swore them off. Lost 45 pounds. Hardest of all, perhaps, was trusting total strangers who introduced themselves as my doctors and nurses and technicians and dietitians and therapists — far from a battalion of warriors, they made up a gentle, life-saving team. They addressed my cancer. I dealt with my psyche. And my family. I can only hope I did as well as they.
Battle cancer? At 67 years of age? At 80? At 8? Other than “following orders,” military language never came into play. If a metaphor were needed, weather provided a more useful lexicon. Weather can surprise, strike hard and then dissipate.
Cancer was akin to a great Nor’easter; once spotted on the radar screen, you batten down the hatches, consult the experts, follow the playbook, gather supplies and community and hope for the best.
You don’t fight weather. You don’t blame its victims, and you don’t put the onus on the stricken.
With cancer, the only real war is the war of words. And even a wordsmith like Barack Obama, ever empathic, could use some re-education.
“Give it hell, John,” is what Mr. Obama tweeted to Senator McCain.