20 March 2018
This we look at asprin and survival of head and neck cancer patients,
Collection and use of medical data, the risks of opioid misuse, the cost of chronic pain to New Zealand, and mental health issues and aHNC diagnosis..#headnecknz #hnc #hnca
Can Aspirin Use Improve Survival in Certain Patients With Head and Neck Cancer?
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin may help improve the chance of survival for some patients with cancer, according to a new study.
The study, published in the Journal of Experimental Medicine, suggests that regular use of aspirin may be effective against some types of head and neck squamous cell carcinoma (HNSCC). For the study, researchers from the University of Pittsburgh School of Medicine and the University of Arizona analyzed a group of 266 patients with HNSCC who had their tumors surgically removed and were treated with adjuvant chemotherapy and/or radiotherapy.
The researchers found that regular aspirin use dramatically improved survival for patients with mutations in a gene called PIK3A, which is the most commonly altered oncogene in HNSCC. Thirty-four percent of all tumors in HNSCC carry mutations that activate PIK3A, according to the study. Twenty-eight percent of the tumors in the study had an activating alteration of the PIK3A gene.
Collection, use of consumer data puts sensitive health information at risk, groups say
The information that consumers share online, including sensitive health data, is being collected, shared with third parties and sold, often without consumers’ awareness.
That is putting consumers’ privacy at risk, according to many federal lawmakers and civil rights groups at a hearing on Capitol Hill this week. Read more...
Patients with head and neck cancer may be at risk for opioid misuse
Jessica D. McDermott
Patients with oral and oropharyngeal cancer appeared likely to receive opioids for pain management during treatment, and a significant number continued to use them 3 and 6 months later, according to a study published in Otolaryngology-Head and Neck Surgery.
“We felt like it was a long-term problem for some of our head and neck patients, but we didn’t know how much of a problem,” Jessica D. McDermott, MD, investigator at University of Colorado Cancer Center and assistant professor at CU School of Medicine, said in a press release. “You shouldn’t need opioids at the 6-month point.” Read more….
Chronic pain comes at a huge financial and emotional cost but New Zealand lacks an action plan
It started with a fractured pelvis which Deb Thompson assumed would "come right" with rest and time - but six years on her chronic pain remains.
Attempts to bring the unseen and lingering condition under control proved fruitless with all her doctors' suggestions and two hip operations making little difference to Thompson's quality of life.
"The mentality is that you can fix everything but some things can't be fixed ... it's really hard to get your head around."
Mental health disorders more common after head and neck cancer diagnosis
Findings from a cohort study of more than 52,000 patients diagnosed with head and neck cancer revealed that the prevalence of mental health disorders increased after they received the cancer diagnosis.
Although prior research has found a link between mental health disorders (MHDs) and head and neck cancer (HNC), large-scale analysis is needed, Neerav Goyal, MD, MPH, from the division of otolaryngology–head and neck surgery, Pennsylvania State University College of Medicine, and colleagues wrote.